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Strain differences in thymic atrophy in rats immunized for EAE correlate with the clinical outcome of immunization
An accumulating body of evidence suggests that development of autoimmune pathologies leads to thymic dysfunction and changes in peripheral T-cell compartment, which, in turn, perpetuate their pathogenesis. To test this hypothesis, thymocyte differentiation/maturation in rats susceptible (Dark Agouti...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080797/ https://www.ncbi.nlm.nih.gov/pubmed/30086167 http://dx.doi.org/10.1371/journal.pone.0201848 |