MicroRNA-19a/b-3p protect the heart from hypertension-induced pathological cardiac hypertrophy through PDE5A

AIM: PDE5A is a leading factor contributing to cGMP signaling and cardiac hypertrophy. However, microRNA-mediated posttranscriptional regulation of PDE5A has not been reported. The aim of this study is to screen the microRNAs that are able to regulate PDE5A and explore the function of the microRNAs...

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Detalles Bibliográficos
Autores principales: Liu, Kun, Hao, Qiongyu, Wei, Jie, Li, Gong-Hao, Wu, Yong, Zhao, Yun-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
ORIGINAL PAPERS: Organ damage
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080882/
https://www.ncbi.nlm.nih.gov/pubmed/29664809
http://dx.doi.org/10.1097/HJH.0000000000001769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080882/
https://www.ncbi.nlm.nih.gov/pubmed/29664809
http://dx.doi.org/10.1097/HJH.0000000000001769

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