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MicroRNA-19a/b-3p protect the heart from hypertension-induced pathological cardiac hypertrophy through PDE5A
AIM: PDE5A is a leading factor contributing to cGMP signaling and cardiac hypertrophy. However, microRNA-mediated posttranscriptional regulation of PDE5A has not been reported. The aim of this study is to screen the microRNAs that are able to regulate PDE5A and explore the function of the microRNAs...
Autores principales: | Liu, Kun, Hao, Qiongyu, Wei, Jie, Li, Gong-Hao, Wu, Yong, Zhao, Yun-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080882/ https://www.ncbi.nlm.nih.gov/pubmed/29664809 http://dx.doi.org/10.1097/HJH.0000000000001769 |
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