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Heat-resistant action potentials require TTX-resistant sodium channels Na(V)1.8 and Na(V)1.9

Damage-sensing nociceptors in the skin provide an indispensable protective function thanks to their specialized ability to detect and transmit hot temperatures that would block or inflict irreversible damage in other mammalian neurons. Here we show that the exceptional capacity of skin C-fiber nocic...

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Detalles Bibliográficos
Autores principales: Touska, Filip, Turnquist, Brian, Vlachova, Viktorie, Reeh, Peter W., Leffler, Andreas, Zimmermann, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080895/
https://www.ncbi.nlm.nih.gov/pubmed/29970412
http://dx.doi.org/10.1085/jgp.201711786