Minimal molecular determinants of isoform-specific differences in efficacy in the HCN channel family

Hyperpolarization-activated, cyclic nucleotide–gated (HCN) channels generate rhythmic activity in the heart and brain. Isoform-specific functional differences reflect the specializations required for the various roles that they play. Despite a high sequence and structural similarity, HCN isoforms di...

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Detalles Bibliográficos
Autores principales: Alvarez-Baron, Claudia P., Klenchin, Vadim A., Chanda, Baron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080897/
https://www.ncbi.nlm.nih.gov/pubmed/29980633
http://dx.doi.org/10.1085/jgp.201812031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080897/
https://www.ncbi.nlm.nih.gov/pubmed/29980633
http://dx.doi.org/10.1085/jgp.201812031

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