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A splenic IgM memory subset with antibacterial specificities is sustained from persistent mucosal responses

To what extent immune responses against the gut flora are compartmentalized within mucosal tissues in homeostatic conditions remains a much-debated issue. We describe here, based on an inducible AID fate-mapping mouse model, that systemic memory B cell subsets, including mainly IgM(+) B cells in spl...

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Detalles Bibliográficos
Autores principales:	Le Gallou, Simon, Zhou, Zhicheng, Thai, Lan-Huong, Fritzen, Remi, de los Aires, Alba Verge, Mégret, Jérôme, Yu, Philipp, Kitamura, Daisuke, Bille, Emmanuelle, Tros, Fabiola, Nassif, Xavier, Charbit, Alain, Weller, Sandra, Weill, Jean-Claude, Reynaud, Claude-Agnès
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080908/ https://www.ncbi.nlm.nih.gov/pubmed/29959173 http://dx.doi.org/10.1084/jem.20180977

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