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Foxp3(+) T reg cells control psoriasiform inflammation by restraining an IFN-I–driven CD8(+) T cell response
Psoriasis is a complex inflammatory skin disease affecting ∼3% of the population worldwide. Although type I interferons (IFN-I) are thought to be involved in its pathogenesis, the details of this relationship remain elusive. Here we show that in a murine model of imiquimod-driven psoriatic skin infl...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080913/ https://www.ncbi.nlm.nih.gov/pubmed/29980582 http://dx.doi.org/10.1084/jem.20172094 |