Foxp3(+) T reg cells control psoriasiform inflammation by restraining an IFN-I–driven CD8(+) T cell response

Psoriasis is a complex inflammatory skin disease affecting ∼3% of the population worldwide. Although type I interferons (IFN-I) are thought to be involved in its pathogenesis, the details of this relationship remain elusive. Here we show that in a murine model of imiquimod-driven psoriatic skin infl...

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Detalles Bibliográficos
Autores principales: Stockenhuber, Krista, Hegazy, Ahmed N., West, Nathaniel R., Ilott, Nicholas E., Stockenhuber, Alexander, Bullers, Samuel J., Thornton, Emily E., Arnold, Isabelle C., Tucci, Andrea, Waldmann, Herman, Ogg, Graham S., Powrie, Fiona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080913/
https://www.ncbi.nlm.nih.gov/pubmed/29980582
http://dx.doi.org/10.1084/jem.20172094

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