CRL4(DCAF2) negatively regulates IL-23 production in dendritic cells and limits the development of psoriasis

The E3 ligase CRL4(DCAF2) is believed to be a pivotal regulator of the cell cycle and is required for mitotic and S phase progression. The NEDD8-targeting drug MLN4924, which inactivates cullin ring-finger ubiquitin ligases (CRLs), has been examined in clinical trials for various types of lymphoma a...

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Detalles Bibliográficos
Autores principales: Huang, Tao, Gao, Zhengjun, Zhang, Yu, Fan, Keqi, Wang, Fei, Li, Yiyuan, Zhong, Jiangyan, Fan, Heng Y., Cao, Qian, Zhou, Jiyong, Xiao, Yichuan, Hu, Hongbo, Jin, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080916/
https://www.ncbi.nlm.nih.gov/pubmed/30018073
http://dx.doi.org/10.1084/jem.20180210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080916/
https://www.ncbi.nlm.nih.gov/pubmed/30018073
http://dx.doi.org/10.1084/jem.20180210

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