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F-Actin nucleated on chromosomes coordinates their capture by microtubules in oocyte meiosis

Capture of each and every chromosome by spindle microtubules is essential to prevent chromosome loss and aneuploidy. In somatic cells, astral microtubules search and capture chromosomes forming lateral attachments to kinetochores. However, this mechanism alone is insufficient in large oocytes. We ha...

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Detalles Bibliográficos
Autores principales: Burdyniuk, Mariia, Callegari, Andrea, Mori, Masashi, Nédélec, François, Lénárt, Péter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080919/
https://www.ncbi.nlm.nih.gov/pubmed/29903878
http://dx.doi.org/10.1083/jcb.201802080