A Ca(2+)-stimulated exosome release pathway in cancer cells is regulated by Munc13-4

Cancer cells secrete copious amounts of exosomes, and elevated intracellular Ca(2+) is critical for tumor progression and metastasis, but the underlying cellular mechanisms are unknown. Munc13-4 is a Ca(2+)-dependent SNAP receptor– and Rab-binding protein required for Ca(2+)-dependent membrane fusio...

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Detalles Bibliográficos
Autores principales: Messenger, Scott W., Woo, Sang Su, Sun, Zhongze, Martin, Thomas F.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080937/
https://www.ncbi.nlm.nih.gov/pubmed/29930202
http://dx.doi.org/10.1083/jcb.201710132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080937/
https://www.ncbi.nlm.nih.gov/pubmed/29930202
http://dx.doi.org/10.1083/jcb.201710132

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