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A Ca(2+)-stimulated exosome release pathway in cancer cells is regulated by Munc13-4
Cancer cells secrete copious amounts of exosomes, and elevated intracellular Ca(2+) is critical for tumor progression and metastasis, but the underlying cellular mechanisms are unknown. Munc13-4 is a Ca(2+)-dependent SNAP receptor– and Rab-binding protein required for Ca(2+)-dependent membrane fusio...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080937/ https://www.ncbi.nlm.nih.gov/pubmed/29930202 http://dx.doi.org/10.1083/jcb.201710132 |