Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance

Growth cones navigate axonal projection in response to guidance cues. However, it is unclear how they can decide the migratory direction by transducing the local spatial cues into protrusive forces. Here we show that knockout mice of Shootin1 display abnormal projection of the forebrain commissural...

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Detalles Bibliográficos
Autores principales: Baba, Kentarou, Yoshida, Wataru, Toriyama, Michinori, Shimada, Tadayuki, Manning, Colleen F, Saito, Michiko, Kohno, Kenji, Trimmer, James S, Watanabe, Rikiya, Inagaki, Naoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080949/
https://www.ncbi.nlm.nih.gov/pubmed/30082022
http://dx.doi.org/10.7554/eLife.34593

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6080949/
https://www.ncbi.nlm.nih.gov/pubmed/30082022
http://dx.doi.org/10.7554/eLife.34593

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