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Role of TNFRSF1A and TNFRSF1B polymorphisms in susceptibility, severity, and therapeutic efficacy of etanercept in human leukocyte antigen-B27-positive Chinese Han patients with ankylosing spondylitis

The successful therapeutic use of anti-TNF biological agents in patients with ankylosing spondylitis (AS) indicates that tumor necrosis factor-α (TNF-α) and tumor necrosis factor receptor (TNFR) genes are involved in the pathogenesis of AS. TNF-α exerts its biological activity by binding to its cell...

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Detalles Bibliográficos
Autores principales: Xing-rong, Wang, Sheng-qian, Xu, Wen, Liu, Shan, Qi, Fa-ming, Pan, Jian-hua, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081148/
https://www.ncbi.nlm.nih.gov/pubmed/30075559
http://dx.doi.org/10.1097/MD.0000000000011677