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Polymorphisms of DNA repair genes are associated with colorectal cancer in patients with Lynch syndrome

BACKGROUND: DNA repair genes are crucial for maintaining genomic stability by preventing mutagenesis and carcinogenesis. The present retrospective cohort study aimed at investigating whether MLH1,APEX1,MUTYH,OGG1,NUDT1,XRCC5, XPA, and ERCC2 single nucleotide polymorphisms (SNPs) are associated with...

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Detalles Bibliográficos
Autores principales: Kamiza, Abram B., Hsieh, Ling‐Ling, Tang, Reiping, Chien, Huei‐Tzu, Lai, Chih‐Hsiung, Chiu, Li‐Ling, Lo, Tsai‐Ping, Hung, Kuan‐Yi, You, Jeng‐Fu, Wang, Wen‐Chang, Hsiung, Chao A., Yeh, Chih‐Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081223/
https://www.ncbi.nlm.nih.gov/pubmed/29664240
http://dx.doi.org/10.1002/mgg3.402