Metformin reverses established lung fibrosis in a bleomycin model

Fibrosis is a pathological result of a dysfunctional repair response to tissue injury and occurs in a number of organs, including the lungs(1). Cellular metabolism regulates tissue repair and remodeling responses to injury(2–4). AMPK is a critical sensor of cellular bioenergetics and controls the sw...

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Detalles Bibliográficos
Autores principales: Rangarajan, Sunad, Bone, Nathaniel B., Zmijewska, Anna A., Jiang, Shaoning, Park, Dae Won, Bernard, Karen, Locy, Morgan L., Ravi, Saranya, Deshane, Jessy, Mannon, Roslyn B., Abraham, Edward, Darley-Usmar, Victor, Thannickal, Victor J., Zmijewski, Jaroslaw W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081262/
https://www.ncbi.nlm.nih.gov/pubmed/29967351
http://dx.doi.org/10.1038/s41591-018-0087-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081262/
https://www.ncbi.nlm.nih.gov/pubmed/29967351
http://dx.doi.org/10.1038/s41591-018-0087-6

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