Positive/Negative Allosteric Modulation Switching in an Umami Taste Receptor (T1R1/T1R3) by a Natural Flavor Compound, Methional

Taste is a vital sensation for vertebrates, enabling the detection of nutritionally important substances or potential toxins. A heteromeric complex of two class C GPCRs, T1R1 and T1R3, was identified as the umami (savory) taste receptor. Amino acids and 5′-ribonucleotides are well known to be natura...

Descripción completa

Detalles Bibliográficos
Autores principales: Toda, Yasuka, Nakagita, Tomoya, Hirokawa, Takatsugu, Yamashita, Yuki, Nakajima, Ayako, Narukawa, Masataka, Ishimaru, Yoshiro, Uchida, Riichiro, Misaka, Takumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081381/
https://www.ncbi.nlm.nih.gov/pubmed/30087430
http://dx.doi.org/10.1038/s41598-018-30315-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081381/
https://www.ncbi.nlm.nih.gov/pubmed/30087430
http://dx.doi.org/10.1038/s41598-018-30315-x

Ejemplares similares