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TSC1 and DEPDC5 regulate HIV-1 latency through the mTOR signaling pathway
The latent reservoir of HIV-1 presents a major barrier to viral eradication. The mechanism of the establishment and maintenance of the latent viral reservoir is not yet fully understood, which hinders the development of effective curative strategies. In this study, we identified two inhibitory genes...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081400/ https://www.ncbi.nlm.nih.gov/pubmed/30087333 http://dx.doi.org/10.1038/s41426-018-0139-5 |