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TSC1 and DEPDC5 regulate HIV-1 latency through the mTOR signaling pathway

The latent reservoir of HIV-1 presents a major barrier to viral eradication. The mechanism of the establishment and maintenance of the latent viral reservoir is not yet fully understood, which hinders the development of effective curative strategies. In this study, we identified two inhibitory genes...

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Detalles Bibliográficos
Autores principales: Jin, Shan, Liao, Qibin, Chen, Jian, Zhang, Linxia, He, Qian, Zhu, Huanzhang, Zhang, Xiaoyan, Xu, Jianqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081400/
https://www.ncbi.nlm.nih.gov/pubmed/30087333
http://dx.doi.org/10.1038/s41426-018-0139-5