Developmental seizures and mortality result from reducing GABA(A) receptor α2-subunit interaction with collybistin

Fast inhibitory synaptic transmission is mediated by γ-aminobutyric acid type A receptors (GABA(A)Rs) that are enriched at functionally diverse synapses via mechanisms that remain unclear. Using isothermal titration calorimetry and complementary methods we demonstrate an exclusive low micromolar bin...

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Detalles Bibliográficos
Autores principales: Hines, Rochelle M., Maric, Hans Michael, Hines, Dustin J., Modgil, Amit, Panzanelli, Patrizia, Nakamura, Yasuko, Nathanson, Anna J., Cross, Alan, Deeb, Tarek, Brandon, Nicholas J., Davies, Paul, Fritschy, Jean-Marc, Schindelin, Hermann, Moss, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081406/
https://www.ncbi.nlm.nih.gov/pubmed/30087324
http://dx.doi.org/10.1038/s41467-018-05481-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081406/
https://www.ncbi.nlm.nih.gov/pubmed/30087324
http://dx.doi.org/10.1038/s41467-018-05481-1

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