Essential role of MED1 in the transcriptional regulation of ER-dependent oncogenic miRNAs in breast cancer

Mediator complex has been extensively shown to regulate the levels of several protein-coding genes; however, its role in the regulation of miRNAs in humans remains unstudied so far. Here we show that MED1, a Mediator subunit in the Middle module of Mediator complex, is overexpressed in breast cancer...

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Detalles Bibliográficos
Autores principales: Nagpal, Neha, Sharma, Shivani, Maji, Sourobh, Durante, Giorgio, Ferracin, Manuela, Thakur, Jitendra K., Kulshreshtha, Ritu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081450/
https://www.ncbi.nlm.nih.gov/pubmed/30087366
http://dx.doi.org/10.1038/s41598-018-29546-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081450/
https://www.ncbi.nlm.nih.gov/pubmed/30087366
http://dx.doi.org/10.1038/s41598-018-29546-9

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