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Inhibition of a K9/K36 demethylase by an H3.3 point mutation found in paediatric glioblastoma
An array of oncogenic histone point mutations have been identified across a number of different cancer studies. It has been suggested that some of these mutant histones can exert their effects by inhibiting epigenetic writers. Here, we report that the H3.3 G34R (glycine to arginine) substitution mut...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081460/ https://www.ncbi.nlm.nih.gov/pubmed/30087349 http://dx.doi.org/10.1038/s41467-018-05607-5 |