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Serotonin depletion causes valproate-responsive manic-like condition and increased hippocampal neuroplasticity that are reversed by stress
Abnormal hippocampal neural plasticity has been implicated in behavioural abnormalities and complex neuropsychiatric conditions, including bipolar disorder (BD). However, the determinants of this neural alteration remain unknown. This work tests the hypothesis that the neurotransmitter serotonin (5-...
Autores principales: | Maddaloni, Giacomo, Migliarini, Sara, Napolitano, Francesco, Giorgi, Andrea, Nazzi, Serena, Biasci, Daniele, De Felice, Alessia, Gritti, Marta, Cavaccini, Anna, Galbusera, Alberto, Franceschi, Sara, Lessi, Francesca, Ferla, Marco La, Aretini, Paolo, Mazzanti, Chiara Maria, Tonini, Raffaella, Gozzi, Alessandro, Usiello, Alessandro, Pasqualetti, Massimo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081464/ https://www.ncbi.nlm.nih.gov/pubmed/30087403 http://dx.doi.org/10.1038/s41598-018-30291-2 |
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