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Monitoring the action of redox-directed cancer therapeutics using a human peroxiredoxin-2-based probe

Redox cancer therapeutics target the increased reliance on intracellular antioxidant systems and enhanced susceptibility to oxidant-induced stress of some cancer cells compared to normal cells. Many of these therapeutics are thought to perturb intracellular levels of the oxidant hydrogen peroxide (H...

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Detalles Bibliográficos
Autores principales: Langford, Troy F., Huang, Beijing K., Lim, Joseph B., Moon, Sun Jin, Sikes, Hadley D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081480/
https://www.ncbi.nlm.nih.gov/pubmed/30087344
http://dx.doi.org/10.1038/s41467-018-05557-y