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Sodium Tanshinone IIA Sulfonate Prevents Angiotensin II-Induced Differentiation of Human Atrial Fibroblasts into Myofibroblasts

Differentiation of atrial fibroblasts into myofibroblasts plays a critical role in atrial fibrosis. Sodium tanshinone IIA sulfonate (DS-201), a water-soluble derivative of tanshinone IIA, has been shown to have potent antifibrotic properties. However, the protective effects of DS-201 on angiotensin...

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Detalles Bibliográficos
Autores principales: Chen, Tangting, Li, Miaoling, Fan, Xuehui, Cheng, Jun, Wang, Liqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081515/
https://www.ncbi.nlm.nih.gov/pubmed/30140368
http://dx.doi.org/10.1155/2018/6712585