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NF-κB-94ins/del ATTG Genotype Contributes to the Susceptibility and Imbalanced Th17 Cells in Patients with Immune Thrombocytopenia

BACKGROUND: The NLRP3 inflammasome plays important roles in the pathogenesis of autoimmune diseases. However, the role of the NLRP3 inflammasome in the pathophysiology of immune thrombocytopenia (ITP) remains unclear. METHODS: RT-PCR was used to examine the polymorphism and expression of genes invol...

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Detalles Bibliográficos
Autores principales: Yu, Jie, Hua, Mingqiang, Zhao, Xueyun, Wang, Rui, Zhong, Chaoqing, Zhang, Chen, Wang, Ruiqing, Li, Guosheng, He, Na, Hou, Ming, Ma, Daoxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081577/
https://www.ncbi.nlm.nih.gov/pubmed/30140708
http://dx.doi.org/10.1155/2018/8170436