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IL-8/CXCR1/2 signalling promotes tumor cell proliferation, invasion and vascular mimicry in glioblastoma

BACKGROUND: Glioblastoma multiforme (GBM) is one of the lethal malignant tumors of the central nervous system. Despite advances made in understanding this complex disease, little has been achieved in improving clinical efficacy towards it. Factors such as chemokines play important role in shaping th...

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Detalles Bibliográficos
Autores principales: Sharma, Ira, Singh, Avninder, Siraj, Fouzia, Saxena, Sunita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081798/
https://www.ncbi.nlm.nih.gov/pubmed/30086759
http://dx.doi.org/10.1186/s12929-018-0464-y