Compromised astrocyte function and survival negatively impact neurons in infantile neuronal ceroid lipofuscinosis

The neuronal ceroid lipofuscinoses (NCLs) are the most common cause of childhood dementia and are invariably fatal. Early localized glial activation occurs in these disorders, and accurately predicts where neuronal loss is most pronounced. Recent evidence suggests that glial dysfunction may contribu...

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Detalles Bibliográficos
Autores principales: Lange, Jenny, Haslett, Luke J., Lloyd-Evans, Emyr, Pocock, Jennifer M., Sands, Mark S., Williams, Brenda P., Cooper, Jonathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081811/
https://www.ncbi.nlm.nih.gov/pubmed/30089511
http://dx.doi.org/10.1186/s40478-018-0575-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081811/
https://www.ncbi.nlm.nih.gov/pubmed/30089511
http://dx.doi.org/10.1186/s40478-018-0575-4

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