Cargando…

Targeting of HER3 with Functional Cooperative miRNAs Enhances Therapeutic Activity in HER2-Overexpressing Breast Cancer Cells

BACKGROUND: The HER3 receptor functions as a major cause of drug resistance in cancer treatment. It is believed that therapeutic targeting of HER3 is required to improve patient outcomes. It is not clear whether a novel strategy with two functional cooperative miRNAs would effectively inhibit erbB3...

Descripción completa

Detalles Bibliográficos
Autores principales: Lyu, Hui, Huang, Jingcao, He, Zhimin, Liu, Bolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081814/
https://www.ncbi.nlm.nih.gov/pubmed/30093840
http://dx.doi.org/10.1186/s12575-018-0081-x