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Inhibition of Shp2 ameliorates monocrotaline-induced pulmonary arterial hypertension in rats
BACKGROUND: Src homology 2 containing protein tyrosine phosphatase (PTP) 2 (Shp2) is a typical tyrosine phosphatase interacting with receptor tyrosine kinase to regulate multiple signaling pathways in diverse pathological processes. Here, we will investigate the effect of Shp2 inhibition on pulmonar...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081862/ https://www.ncbi.nlm.nih.gov/pubmed/30086741 http://dx.doi.org/10.1186/s12890-018-0700-y |