Cargando…

Meta-analysis of exome array data identifies six novel genetic loci for lung function

Background: Over 90 regions of the genome have been associated with lung function to date, many of which have also been implicated in chronic obstructive pulmonary disease. Methods: We carried out meta-analyses of exome array data and three lung function measures: forced expiratory volume in one sec...

Descripción completa

Detalles Bibliográficos
Autores principales: Jackson, Victoria E., Latourelle, Jeanne C., Wain, Louise V., Smith, Albert V., Grove, Megan L., Bartz, Traci M., Obeidat, Ma'en, Province, Michael A., Gao, Wei, Qaiser, Beenish, Porteous, David J., Cassano, Patricia A., Ahluwalia, Tarunveer S., Grarup, Niels, Li, Jin, Altmaier, Elisabeth, Marten, Jonathan, Harris, Sarah E., Manichaikul, Ani, Pottinger, Tess D., Li-Gao, Ruifang, Lind-Thomsen, Allan, Mahajan, Anubha, Lahousse, Lies, Imboden, Medea, Teumer, Alexander, Prins, Bram, Lyytikäinen, Leo-Pekka, Eiriksdottir, Gudny, Franceschini, Nora, Sitlani, Colleen M., Brody, Jennifer A., Bossé, Yohan, Timens, Wim, Kraja, Aldi, Loukola, Anu, Tang, Wenbo, Liu, Yongmei, Bork-Jensen, Jette, Justesen, Johanne M., Linneberg, Allan, Lange, Leslie A., Rawal, Rajesh, Karrasch, Stefan, Huffman, Jennifer E., Smith, Blair H., Davies, Gail, Burkart, Kristin M., Mychaleckyj, Josyf C., Bonten, Tobias N., Enroth, Stefan, Lind, Lars, Brusselle, Guy G., Kumar, Ashish, Stubbe, Beate, Kähönen, Mika, Wyss, Annah B., Psaty, Bruce M., Heckbert, Susan R., Hao, Ke, Rantanen, Taina, Kritchevsky, Stephen B., Lohman, Kurt, Skaaby, Tea, Pisinger, Charlotta, Hansen, Torben, Schulz, Holger, Polasek, Ozren, Campbell, Archie, Starr, John M., Rich, Stephen S., Mook-Kanamori, Dennis O., Johansson, Åsa, Ingelsson, Erik, Uitterlinden, André G., Weiss, Stefan, Raitakari, Olli T., Gudnason, Vilmundur, North, Kari E., Gharib, Sina A., Sin, Don D., Taylor, Kent D., O'Connor, George T., Kaprio, Jaakko, Harris, Tamara B., Pederson, Oluf, Vestergaard, Henrik, Wilson, James G., Strauch, Konstantin, Hayward, Caroline, Kerr, Shona, Deary, Ian J., Barr, R. Graham, de Mutsert, Renée, Gyllensten, Ulf, Morris, Andrew P., Ikram, M. Arfan, Probst-Hensch, Nicole, Gläser, Sven, Zeggini, Eleftheria, Lehtimäki, Terho, Strachan, David P., Dupuis, Josée, Morrison, Alanna C., Hall, Ian P., Tobin, Martin D., London, Stephanie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6081985/
https://www.ncbi.nlm.nih.gov/pubmed/30175238
http://dx.doi.org/10.12688/wellcomeopenres.12583.3