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Atorvastatin mitigates cyclophosphamide-induced hepatotoxicity via suppression of oxidative stress and apoptosis in rat model

Cyclophosphamide (CP), as a chemotherapy drug, induces hepatotoxicity through causing oxidative stress. Atorvastatin (ATV) at a low dose has antioxidant and anti-inflammatory properties. The present study was designed to investigate the protective effects of ATV against CP-induced hepatotoxicity in...

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Detalles Bibliográficos
Autores principales: Hamzeh, Maedeh, Hosseinimehr, Seyed Jalal, Khalatbary, Ali Reza, Mohammadi, Hamid Reza, Dashti, Ayat, Amiri, Fereshteh Talebpour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082033/
https://www.ncbi.nlm.nih.gov/pubmed/30271446
http://dx.doi.org/10.4103/1735-5362.236837