Cargando…

Atorvastatin mitigates cyclophosphamide-induced hepatotoxicity via suppression of oxidative stress and apoptosis in rat model

Cyclophosphamide (CP), as a chemotherapy drug, induces hepatotoxicity through causing oxidative stress. Atorvastatin (ATV) at a low dose has antioxidant and anti-inflammatory properties. The present study was designed to investigate the protective effects of ATV against CP-induced hepatotoxicity in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hamzeh, Maedeh, Hosseinimehr, Seyed Jalal, Khalatbary, Ali Reza, Mohammadi, Hamid Reza, Dashti, Ayat, Amiri, Fereshteh Talebpour
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082033/ https://www.ncbi.nlm.nih.gov/pubmed/30271446 http://dx.doi.org/10.4103/1735-5362.236837

Ejemplares similares

Atorvastatin attenuates the ovarian damage induced by cyclophosphamide in rat: An experimental study
por: Hamzeh, Maedeh, et al.
Publicado: (2018)

Cerium Oxide Nanoparticles Protect Cyclophosphamide-induced Testicular Toxicity in Mice
por: Hamzeh, Maedeh, et al.
Publicado: (2019)

Zataria multiflora ameliorates cisplatin-induced testicular damage via suppression of oxidative stress and apoptosis in a mice model
por: Karimi, Shokooh, et al.
Publicado: (2018)

Alleviation of cisplatin‐induced hepatotoxicity by gliclazide: Involvement of oxidative stress and caspase‐3 activity
por: Taghizadeh, Fatemeh, et al.
Publicado: (2021)

Deltamethrin-Induced Hepatotoxicity and Virgin Olive Oil Consumption: An Experimental Study
por: Khalatbary, Ali Reza, et al.
Publicado: (2017)

Sinapic acid attenuates cyclophosphamide-induced liver toxicity in mice by modulating oxidative stress, NF-κB, and caspase-3
por: Rezaei, Shiva, et al.
Publicado: (2023)

Juglans Regia L. Leaf Extract Attenuates Diabetic Nephropathy Progression in Experimental Diabetes: An Immunohistochemical Study
por: Nasiry, Davood, et al.
Publicado: (2019)

Homing of adipose stem cells on the human amniotic membrane as a scaffold: A histological study
por: Zarei, Hooman, et al.
Publicado: (2020)

Data on the in vitro and in vivo anti-tumor effects of itraconazole, paclitaxel, and the two in combination in HT-29 and YM-1 cancer cell line and HT-29 colon cancer xenograft models
por: Ghadi, Mahdi, et al.
Publicado: (2021)

(99m)Tc-Glucarate for assessment of paclitaxel therapy in human ovarian cancer in mice
por: Sadeghi, Hossein, et al.
Publicado: (2018)

Protective effects of methanolic extract of Juglans regia L. leaf on streptozotocin-induced diabetic peripheral neuropathy in rats
por: Nasiry, Davood, et al.
Publicado: (2017)

Administration of zinc against arsenic-induced nephrotoxicity during gestation and lactation in rat model
por: Nasiry Zarrin Ghabaee, Davood, et al.
Publicado: (2017)

Rutin mitigates perfluorooctanoic acid-induced liver injury via modulation of oxidative stress, apoptosis, and inflammation
por: Naderi, Maloos, et al.
Publicado: (2023)

Effects of Olive Oil supplementation on Sodium Arsenate-induced Hepatotoxicity in Mice
por: Mohammadian, Mona, et al.
Publicado: (2018)

Atorvastatin Sensitizes Breast and Lung Cancer Cells to Ionizing Radiation
por: Hosseinimehr, Seyed Jalal, et al.
Publicado: (2020)

Effects of Benzo(a)pyrene on the endometrial receptivity and embryo implantation in mice: An experimental study
por: Mardanshahi, Zeinab, et al.
Publicado: (2019)

Low-dose cyclophosphamide-induced acute hepatotoxicity
por: Subramaniam, S. Ravih, et al.
Publicado: (2013)

Low-Dose Cyclophosphamide Associated With Hyponatremia and Hepatotoxicity
por: DeChiara, James R, et al.
Publicado: (2023)

Celecoxib mitigates genotoxicity induced by ionizing radiation in human blood lymphocytes
por: Hosseinimehr, Seyed Jalal, et al.
Publicado: (2017)

Statin therapy and hepatotoxicity: Appraisal of the safety profile of atorvastatin in hyperlipidemic patients
por: Kalantari, Saeed, et al.
Publicado: (2014)

Recurrence and Severe Worsening of Hepatotoxicity After Reintroduction of Atorvastatin in Combination With Ezetimibe
por: Bergland Ellingsen, Silje, et al.
Publicado: (2017)

The protective effects of trace elements against side effects induced by ionizing radiation
por: Hosseinimehr, Seyed Jalal
Publicado: (2015)

Coadministration of Atorvastatin and Amiodarone Increases the Risk of Pulmonary Fibrosis in Rats
por: Nasri, Hamid-Reza, et al.
Publicado: (2016)

Atorvastatin attenuates ethanol-induced hepatotoxicity via antioxidant and anti-inflammatory mechanisms
por: Zamani, Ehsan, et al.
Publicado: (2017)

Association of atorvastatin with the risk of hepatotoxicity: a pilot prescription sequence symmetry analysis
por: Zhang, Haiping, et al.
Publicado: (2019)

Atorvastatin for Prevention of Amikacin-induced Electrolytes Imbalances; a Randomized Clinical Trial
por: Heydari, Behrooz, et al.
Publicado: (2016)

Dose-Dependent Effect of Hydrogen Sulfide in Cyclophosphamide-Induced Hepatotoxicity in Rats
por: Özatik, Fikriye Yasemin, et al.
Publicado: (2023)

Protective effects of melatonin solid lipid nanoparticles on testis histology after testicular trauma in rats
por: Mirhoseini, Mehri, et al.
Publicado: (2019)

The Radiolabeled HER3 Targeting Molecules for Tumor Imaging
por: Molavipordanjani, Sajjad, et al.
Publicado: (2021)

Radiation-Induced Cancer Risks from Computed Tomographic Scans During COVID-19 Pandemic
por: Majidi, Hadi, et al.
Publicado: (2022)

Atorvastatin Downregulates In Vitro Methyl Methanesulfonate and Cyclophosphamide Alkylation-Mediated Cellular and DNA Injuries
por: Araujo-Lima, Carlos F., et al.
Publicado: (2018)

Galangin Activates Nrf2 Signaling and Attenuates Oxidative Damage, Inflammation, and Apoptosis in a Rat Model of Cyclophosphamide-Induced Hepatotoxicity
por: Aladaileh, Saleem H., et al.
Publicado: (2019)

Genistein Ameliorates Cyclophosphamide - Induced Hepatotoxicity by Modulation of Oxidative Stress and Inflammatory Mediators
por: Mansour, Dina F., et al.
Publicado: (2017)

Effect of Malva sylvestris cream on burn injury and wounds in rats
por: Nasiri, Ebrahim, et al.
Publicado: (2015)

Immunohistochemical and Electron Microscopic Study of the Inhibitory Effects of Olive Oil Polyphenol on Dexamethasone-Induced Apoptosis
por: Khalatbary, Ali Reza, et al.
Publicado: (2017)

Resveratrol Sensitizes Selectively Thyroid Cancer Cell to 131-Iodine Toxicity
por: Hosseinimehr, Seyed Jalal, et al.
Publicado: (2014)

Radiosensitive effect of curcumin on thyroid cancer cell death induced by radioiodine-131
por: Hosseinimehr, Seyed Jalal, et al.
Publicado: (2014)

Atorvastatin Induces Hepatotoxicity in Diabetic Rats via Oxidative Stress, Inflammation, and Anti-Apoptotic Pathway
por: Zeng, Hanqing, et al.
Publicado: (2019)

Aphallia: Report of three cases and literature review
por: Talebpour Amiri, Fereshteh, et al.
Publicado: (2016)

The effect of aqueous cinnamon extract on the apoptotic process in acute myeloid leukemia HL-60 cells
por: Assadollahi, Vahideh, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_d0t9dnrkj5pqilhvmpdg6vif4h