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Structural basis for the regulation of inositol trisphosphate receptors by Ca(2+) and IP(3)

Inositol trisphosphate receptors (IP(3)R) are ubiquitous Ca(2+)-permeable channels that mediate release of Ca(2+) from the endoplasmic reticulum to regulate numerous processes including cell division, cell death, differentiation and fertilization. IP(3)R is activated by both IP(3) and its permeant i...

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Detalles Bibliográficos
Autores principales: Paknejad, Navid, Hite, Richard K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082148/
https://www.ncbi.nlm.nih.gov/pubmed/30013099
http://dx.doi.org/10.1038/s41594-018-0089-6