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Structural basis for the regulation of inositol trisphosphate receptors by Ca(2+) and IP(3)
Inositol trisphosphate receptors (IP(3)R) are ubiquitous Ca(2+)-permeable channels that mediate release of Ca(2+) from the endoplasmic reticulum to regulate numerous processes including cell division, cell death, differentiation and fertilization. IP(3)R is activated by both IP(3) and its permeant i...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082148/ https://www.ncbi.nlm.nih.gov/pubmed/30013099 http://dx.doi.org/10.1038/s41594-018-0089-6 |