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Identification of potential target genes of USP22 via ChIP-seq and RNA-seq analysis in HeLa cells
The ubiquitin-specific protease 22 (USP22) is an oncogene and its expression is upregulated in many types of cancer. In the nucleus, USP22 functions as one subunit of the SAGA to regulate gene transcription. However, the genome-wide USP22 binding sites and its direct target genes are yet clear. In t...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Genética
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082230/ https://www.ncbi.nlm.nih.gov/pubmed/30088609 http://dx.doi.org/10.1590/1678-4685-GMB-2017-0164 |