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Glutathione depletion triggers actin cytoskeleton changes via actin-binding proteins

The importance of glutathione (GSH) in alternative cellular roles to the canonically proposed, were analyzed in a model unable to synthesize GSH. Gene expression analysis shows that the regulation of the actin cytoskeleton pathway is strongly impacted by the absence of GSH. To test this hypothesis,...

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Detalles Bibliográficos
Autores principales: Zepeta-Flores, Nahum, Valverde, Mahara, Lopez-Saavedra, Alejandro, Rojas, Emilio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082235/
https://www.ncbi.nlm.nih.gov/pubmed/29870570
http://dx.doi.org/10.1590/1678-4685-GMB-2017-0158