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Cranberry-derived proanthocyanidins induce a differential transcriptomic response within Candida albicans urinary biofilms

Candida albicans is one of the most common causes of hospital-acquired urinary tract infections (UTIs). However, azoles are poorly active against biofilms, echinocandins do not achieve clinically useful urinary concentrations, and amphotericin B exhibits severe toxicities. Thus, novel strategies are...

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Detalles Bibliográficos
Autores principales: Sundararajan, Anitha, Rane, Hallie S., Ramaraj, Thiruvarangan, Sena, Johnny, Howell, Amy B., Bernardo, Stella M., Schilkey, Faye D., Lee, Samuel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082538/
https://www.ncbi.nlm.nih.gov/pubmed/30089157
http://dx.doi.org/10.1371/journal.pone.0201969