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A combined approach with gene-wise normalization improves the analysis of RNA-seq data in human breast cancer subtypes

Breast cancer (BC) is increasing in incidence and resistance to treatment worldwide. The challenges in limited therapeutic options and poor survival outcomes in BC subtypes persist because of its molecular heterogeneity and resistance to standard endocrine therapy. Recently, high throughput RNA sequ...

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Detalles Bibliográficos
Autores principales: Li, Xiaohong, Rouchka, Eric C., Brock, Guy N., Yan, Jun, O’Toole, Timothy E., Tieri, David A., Cooper, Nigel G. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082555/
https://www.ncbi.nlm.nih.gov/pubmed/30089167
http://dx.doi.org/10.1371/journal.pone.0201813