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A combined approach with gene-wise normalization improves the analysis of RNA-seq data in human breast cancer subtypes
Breast cancer (BC) is increasing in incidence and resistance to treatment worldwide. The challenges in limited therapeutic options and poor survival outcomes in BC subtypes persist because of its molecular heterogeneity and resistance to standard endocrine therapy. Recently, high throughput RNA sequ...
Autores principales: | Li, Xiaohong, Rouchka, Eric C., Brock, Guy N., Yan, Jun, O’Toole, Timothy E., Tieri, David A., Cooper, Nigel G. F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082555/ https://www.ncbi.nlm.nih.gov/pubmed/30089167 http://dx.doi.org/10.1371/journal.pone.0201813 |
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