Proteasome inhibition induces IKK-dependent interleukin-8 expression in triple negative breast cancer cells: Opportunity for combination therapy

Triple negative breast cancer (TNBC) cells express increased levels of the pro-inflammatory and pro-angiogenic chemokine interleukin-8 (IL-8, CXCL8), which promotes their proliferation and migration. Because TNBC patients are unresponsive to current targeted therapies, new therapeutic strategies are...

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Detalles Bibliográficos
Autores principales: Uddin, Mohammad M., Zou, Yue, Sharma, Tamanna, Gatla, Himavanth R., Vancurova, Ivana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082561/
https://www.ncbi.nlm.nih.gov/pubmed/30089134
http://dx.doi.org/10.1371/journal.pone.0201858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082561/
https://www.ncbi.nlm.nih.gov/pubmed/30089134
http://dx.doi.org/10.1371/journal.pone.0201858

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