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Proteasome inhibition induces IKK-dependent interleukin-8 expression in triple negative breast cancer cells: Opportunity for combination therapy
Triple negative breast cancer (TNBC) cells express increased levels of the pro-inflammatory and pro-angiogenic chemokine interleukin-8 (IL-8, CXCL8), which promotes their proliferation and migration. Because TNBC patients are unresponsive to current targeted therapies, new therapeutic strategies are...
Autores principales: | Uddin, Mohammad M., Zou, Yue, Sharma, Tamanna, Gatla, Himavanth R., Vancurova, Ivana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082561/ https://www.ncbi.nlm.nih.gov/pubmed/30089134 http://dx.doi.org/10.1371/journal.pone.0201858 |
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