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HIV induces synaptic hyperexcitation via cGMP-dependent protein kinase II activation in the FIV infection model

Over half of individuals infected with human immunodeficiency virus (HIV) suffer from HIV-associated neurocognitive disorders (HANDs), yet the molecular mechanisms leading to neuronal dysfunction are poorly understood. Feline immunodeficiency virus (FIV) naturally infects cats and shares its structu...

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Detalles Bibliográficos
Autores principales: Sztukowski, Keira, Nip, Kaila, Ostwald, Paige N., Sathler, Matheus F., Sun, Julianna L., Shou, Jiayi, Jorgensen, Emily T., Brown, Travis E., Elder, John H., Miller, Craig, Hofmann, Franz, VandeWoude, Sue, Kim, Seonil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082575/
https://www.ncbi.nlm.nih.gov/pubmed/30052626
http://dx.doi.org/10.1371/journal.pbio.2005315