Cargando…
HIV induces synaptic hyperexcitation via cGMP-dependent protein kinase II activation in the FIV infection model
Over half of individuals infected with human immunodeficiency virus (HIV) suffer from HIV-associated neurocognitive disorders (HANDs), yet the molecular mechanisms leading to neuronal dysfunction are poorly understood. Feline immunodeficiency virus (FIV) naturally infects cats and shares its structu...
Autores principales: | Sztukowski, Keira, Nip, Kaila, Ostwald, Paige N., Sathler, Matheus F., Sun, Julianna L., Shou, Jiayi, Jorgensen, Emily T., Brown, Travis E., Elder, John H., Miller, Craig, Hofmann, Franz, VandeWoude, Sue, Kim, Seonil |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082575/ https://www.ncbi.nlm.nih.gov/pubmed/30052626 http://dx.doi.org/10.1371/journal.pbio.2005315 |
Ejemplares similares
-
Applications of the FIV Model to Study HIV Pathogenesis
por: Miller, Craig, et al.
Publicado: (2018) -
Pathogenesis of oral FIV infection
por: Miller, Craig, et al.
Publicado: (2017) -
FIV vaccine with receptor epitopes results in neutralizing antibodies but does not confer resistance to challenge
por: Miller, Craig, et al.
Publicado: (2018) -
Brain region-specific effects of cGMP-dependent kinase II knockout on AMPA receptor trafficking and animal behavior
por: Kim, Seonil, et al.
Publicado: (2016) -
FIV cross-species transmission: An evolutionary prospective
por: Troyer, Jennifer L., et al.
Publicado: (2008)