Kisspeptin/GPR54 signaling restricts antiviral innate immune response through regulating calcineurin phosphatase activity

G protein–coupled receptor 54 (GPR54), the key receptor for the neuropeptide hormone kisspeptin, plays essential roles in regulating puberty development and cancer metastasis. However, its role in the antiviral innate immune response is unknown. We report that virus-induced type I interferon (IFN-I)...

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Detalles Bibliográficos
Autores principales: Huang, Hongjun, Xiong, Qingqing, Wang, Ning, Chen, Ruoyu, Ren, Hua, Siwko, Stefan, Han, Honghui, Liu, Mingyao, Qian, Min, Du, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082648/
https://www.ncbi.nlm.nih.gov/pubmed/30101190
http://dx.doi.org/10.1126/sciadv.aas9784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082648/
https://www.ncbi.nlm.nih.gov/pubmed/30101190
http://dx.doi.org/10.1126/sciadv.aas9784

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