Presenilin1 regulates Th1 and Th17 effector responses but is not required for experimental autoimmune encephalomyelitis

Multiple Sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS) where pathology is thought to be regulated by autoreactive T cells of the Th1 and Th17 phenotype. In this study we sought to understand the functions of Presenilin 1 (PSEN1) in regulating T cell effe...

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Detalles Bibliográficos
Autores principales: Cummings, Matthew, Arumanayagam, Anitha Christy Sigamani, Zhao, Picheng, Kannanganat, Sunil, Stuve, Olaf, Karandikar, Nitin J., Eagar, Todd N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082653/
https://www.ncbi.nlm.nih.gov/pubmed/30089166
http://dx.doi.org/10.1371/journal.pone.0200752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082653/
https://www.ncbi.nlm.nih.gov/pubmed/30089166
http://dx.doi.org/10.1371/journal.pone.0200752

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