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Efficient formation of inert Bi-213 chelates by tetraphosphorus acid analogues of DOTA: towards improved alpha-therapeutics

BACKGROUND: The recently growing interest in targeted alpha-therapy (TAT) calls for improvement of the labelling chemistry of the corresponding radionuclides. (213)Bi(III) is a short-lived alpha emitter which emits only one alpha particle in its decay chain. Hence, it might be safer in application t...

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Detalles Bibliográficos
Autores principales: Šimeček, Jakub, Hermann, Petr, Seidl, Christof, Bruchertseifer, Frank, Morgenstern, Alfred, Wester, Hans-Jürgen, Notni, Johannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082748/
https://www.ncbi.nlm.nih.gov/pubmed/30091088
http://dx.doi.org/10.1186/s13550-018-0431-3