Palladium prompted on-demand cysteine chemistry for the synthesis of challenging and uniquely modified proteins

Organic chemistry allows for the modification and chemical preparation of protein analogues for various studies. The thiolate side chain of the Cys residue has been a key functionality in these ventures. In order to generate complex molecular targets, there is a particular need to incorporate orthog...

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Detalles Bibliográficos
Autores principales: Jbara, Muhammad, Laps, Shay, Morgan, Michael, Kamnesky, Guy, Mann, Guy, Wolberger, Cynthia, Brik, Ashraf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082840/
https://www.ncbi.nlm.nih.gov/pubmed/30089783
http://dx.doi.org/10.1038/s41467-018-05628-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082840/
https://www.ncbi.nlm.nih.gov/pubmed/30089783
http://dx.doi.org/10.1038/s41467-018-05628-0

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