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Palladium prompted on-demand cysteine chemistry for the synthesis of challenging and uniquely modified proteins
Organic chemistry allows for the modification and chemical preparation of protein analogues for various studies. The thiolate side chain of the Cys residue has been a key functionality in these ventures. In order to generate complex molecular targets, there is a particular need to incorporate orthog...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082840/ https://www.ncbi.nlm.nih.gov/pubmed/30089783 http://dx.doi.org/10.1038/s41467-018-05628-0 |