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Biochemical analyses reveal amino acid residues critical for cell cycle-dependent phosphorylation of human Cdc14A phosphatase by cyclin-dependent kinase 1

Cdc14 enzymes compose a family of highly conserved phosphatases that are present in a wide range of organisms, including yeast and humans, and that preferentially reverse the phosphorylation of Cyclin-Dependent Kinase (Cdk) substrates. The budding yeast Cdc14 orthologue has essential functions in th...

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Detalles Bibliográficos
Autores principales: Ovejero, Sara, Ayala, Patricia, Malumbres, Marcos, Pimentel-Muiños, Felipe X., Bueno, Avelino, Sacristán, María P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082843/
https://www.ncbi.nlm.nih.gov/pubmed/30089874
http://dx.doi.org/10.1038/s41598-018-30253-8