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Biochemical analyses reveal amino acid residues critical for cell cycle-dependent phosphorylation of human Cdc14A phosphatase by cyclin-dependent kinase 1
Cdc14 enzymes compose a family of highly conserved phosphatases that are present in a wide range of organisms, including yeast and humans, and that preferentially reverse the phosphorylation of Cyclin-Dependent Kinase (Cdk) substrates. The budding yeast Cdc14 orthologue has essential functions in th...
Autores principales: | Ovejero, Sara, Ayala, Patricia, Malumbres, Marcos, Pimentel-Muiños, Felipe X., Bueno, Avelino, Sacristán, María P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082843/ https://www.ncbi.nlm.nih.gov/pubmed/30089874 http://dx.doi.org/10.1038/s41598-018-30253-8 |
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